Research Institute for 

Pharmacy & Biochemistry

13 July 2020
Lecturer profile

Natalia Csóková, Ph.D. 

Ms. Csóková graduated from the Faculty of Chemical Technology of the Slovac University of Technology in Bratislava, where she studied biochemistry and microbiology. She completed her postgradual course in molecular biology at the Institute of Neuroimmunology of the Slovak Academy of Science in Bratislava and defended her doctoral thesis in 2004. In 2004-2006 she worked in Axon Neuroscience GmbH (Austria) and continued scientific work within postdoctoral studies in the mentioned institute. In 2007, after completion of its postdoctoral research Ms. Csóková was employed in the R&D Division of Zentiva (Prague), where she worked in the Biocorrelation Section until 2010. From 2011 she is a Medical & Reimbursement Manager in Nutricia, s.r.o.

The professional interests of Ms. Csóková include immunology (preparation and isolation of monoclonal and polyclonal antibodies, immunoprecipitation, radioimmunoassay, ELISA, Western blotting), biochemistry (isolation and purification of recombinant proteins, structure determination of protein complexes, enzyme analysis), tissue cultures, cell isolation, crystallization techniques and X-ray analysis, dissolution techniques of substances and drug formulations and in vitro/in vivo correlations.

Selected publications

Matúšková, M.; Csóková, N.; Filipčík, P.; Hanušovská, E.; Bíreš, J.; Cabadaj, R.; Kontsek, P.; Novák, M. First confirmed sheep scrapie with A136R154Q171 genotype in Slovakia. Acta Virol. 2003, 47, 195-198.

Csóková, N.; Škrabana, R.; Liebig, H.D.; Mederlyová, A.; Kontsek, P.; Novák, M. Rapid purification of truncated tau proteins: model approach to purification of functionally active fragments of disordered proteins, implication for neurodegenerative diseases. Protein Expr. Purif. 2004, 35, 366-372.

Csóková, N.; Škrabana, R.; Urbániková, L.; Kováčech, B.; Popov, A.; Ševčík, J.; Novák, M. Preparation, Crystallization and Preliminary X-Ray Analysis of the Fab Fragment of Monoclonal Antibody MN423, Revealing the Structural Aspects of Alzheimer’s Paired Helical Filaments. Protein Pept. Lett. 2006, 13, 941-944.

Škrabana, R.; Škrabanová, M.; Csóková, N.; Ševčík, J.; Novák, M. Intrinsically disordered tau protein in Alzheimer's tangles: a coincidence or a rule? Bratisl. Med. J. 2006, 107, 354-358.

Ševčík, J.; Škrabana, R.; Dvorský, R.; Csóková, N.; Iqbal, K.; Novák, M. X-Ray structure of the PHF core C-terminus: insight into the folding of the intrinsically disordered protein tau in Alzheimer's disease. FEBS Lett. 2007, 581, 5872-5878.